For dermatology & aesthetic clinics
Derma cosmetics, MTS medical devices, skin boosters and dermal fillers from Korea's leading manufacturers — sourced, verified and delivered by APLE.
APLE is a Korea-based B2B supplier and exporter of professional K-Aesthetics products for licensed dermatology clinics, aesthetic clinics and authorized distributors. APLE supplies Korean dermal fillers, skin boosters, MTS devices, derma cosmetics and professional treatment products sourced from Korean manufacturers.
More about APLEFrom collagen-stimulating fillers to post-treatment skincare — a complete, protocol-ready line-up.
PLLA, CaHA+ and cross-linked HA body fillers.
Exosome, PDRN, PN, NAD+ and collagen boosters.
Wireless MTS pens, booster ampoules and pigments.
Spicule peels from mild to strong intensity.
Non-comedogenic home & back-bar care.
Tap any product to see ingredients, packaging and treatment specs.
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Skin Booster
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Skin BoosterMTS & Device
MTS & DevicePeelingDerma CosmeticProduct documentation may include MFDS, CE, CPNP, MoCRA or other market-specific documentation where applicable. Certification and registration status varies by product and destination country.
Professional pricing for licensed dermatology and aesthetic clinics, with flexible volumes for both domestic and export orders.
Ready-to-use treatment programs, dilution guides and application techniques so your team can deliver consistent results from day one.
A collection of premium aesthetic products by Colemedbio — collagen stimulators, hybrid fillers and regenerative boosters engineered for long-lasting, natural results.
TOSCANA EXO PRO+ — rate of improvement after 4 weeks of use.
Source: manufacturer's clinical test data (Colemedbio). Individual results may vary.
Step-by-step combinations of cleansing, treatment and post-care products.
Brightening care for dull, uneven skin tone.
Deep nourishment and moisture for dehydrated skin.
Elasticity and firmness with exosome and PDRN.
Scalp care with REGLORY EXO+ HAIR.
Acne and scar management for first-time peel patients.
Strong exfoliation for severe acne and scar improvement.
Short, factual explanations of the actives and technologies in our catalog.
A PLLA (poly-L-lactic acid) filler is a biodegradable collagen stimulator. Instead of adding volume directly, its microparticles trigger the skin's own collagen production, restoring volume gradually over several sessions with results lasting about 18–24 months. Example: TOSCANA PLLA.
An HA filler gives immediate volume but no collagen stimulation and typically lasts around a year. A CaHA + cross-linked HA hybrid combines immediate HA correction with long-term collagen synthesis from calcium hydroxyapatite, shows no migration and can still be dissolved with hyaluronidase. Example: TOSCANA CaHA+.
PDRN (polydeoxyribonucleotide) is a DNA-derived molecule, usually extracted from salmon, that supports tissue repair and regeneration by activating fibroblasts and collagen production. It is used for skin regeneration, post-acne recovery and anti-inflammatory care. Examples: TOSCANA PRO+, TOSCANA EXO PRO+.
An exosome skin booster delivers nano-sized vesicles that carry growth factors and signalling molecules to support regeneration, hydration and skin-tone improvement. They are either human adipose stem cell–derived or plant-derived (e.g. Centella Asiatica) and are applied with MTS. Example: REGLORY EXO+.
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme that powers cellular energy (ATP), DNA repair and sirtuin activity. Its levels decline with age, so NAD+ boosters aim to restore skin vitality and slow visible aging. Examples: REGLORY NAD+ NMN, TOSCANA PRO+.
A spicule peel uses microscopic, mineral-rich spicules from coral calcium that embed in the skin for 36–48 hours, stimulating circulation and cell turnover without chemical acids. Intensity is adjusted from mild to strong by the amount of powder and rubbing time. Examples: Seanergy Peel, Peelieve Peeling.
Dermal fillers and medical devices are supplied only to licensed medical professionals, dermatology clinics and aesthetic businesses. Derma cosmetics are available to clinics, spas and authorised resellers.
Email [email protected] with your clinic name, country and the products you are interested in. We will reply with a price list and minimum order details.
We handle both domestic (Korea) and export orders. Availability depends on each product's registration status in your country — contact us and we will confirm.
Yes. Full English catalogs and treatment protocols are available on request, together with the certification or registration documents that apply to each product (for example MFDS, CE, CPNP or MoCRA). Status varies by product and destination country.
We share manufacturer protocols — dilution, application depth and post-treatment care — and can arrange product training for partner clinics.
Get the full catalog and wholesale price list for your clinic.
