For dermatology & aesthetic clinics
YVOIRE, Neuramis, The Chaeum, e.p.t.q., Elravie, VOM and TOSCANA — Korea's leading filler brands, sourced, documented and exported by APLE to licensed clinics and distributors.
APLE is a Korea-based B2B exporter of Korean dermal fillers for licensed dermatology clinics, aesthetic clinics and authorized distributors outside Korea. APLE supplies YVOIRE, Neuramis, The Chaeum, e.p.t.q., Elravie, VOM and TOSCANA fillers sourced from Korean manufacturers and their authorized distributors.
More about APLEFrom fine lines to facial contouring and body volume — choose a brand to see every product and its specifications.
Classic, Volume & Contour, with lidocaine
Monophasic HA — 5 grades, SHAPE technology
No.2, No.3 & No.4 — BDDE < 2 ppm
S100, S300 & S500 — 24 mg/mL, MoD ~1%
Premier Light-L, Deep Line-L, Ultra Volume-L
Light, Intensive & Volume — multi-layered phasic
PLLA, CaHA+ & HA body fillers
Tap any product to see concentration, packaging and indication by depth.
Dermal Filler
Dermal Filler
Dermal FillerDermal FillerDermal FillerDermal FillerDermal FillerFillers sourced from Korean manufacturers and their authorized distributors, with MFDS licences, CE certificates and other documents where applicable. Registration status varies by product and country.
Combine YVOIRE, Neuramis, The Chaeum, e.p.t.q., Elravie, VOM and TOSCANA in one shipment, with wholesale pricing for importers and clinics.
English instructions for use, indication by depth and manufacturer injection guides for every product line.
A Korean filler collection by Colemedbio — a PLLA collagen stimulator, a CaHA + HA hybrid and cross-linked HA body fillers. Supplied for export only.
Short, factual answers about the filler types and technologies in our line-up.
A PLLA (poly-L-lactic acid) filler is a biodegradable collagen stimulator. Instead of adding volume directly, its microparticles trigger the skin's own collagen production, restoring volume gradually over several sessions with results lasting about 18–24 months. Example: TOSCANA PLLA.
An HA filler gives immediate volume but no collagen stimulation. A CaHA + cross-linked HA hybrid combines immediate HA correction with collagen synthesis from calcium hydroxyapatite, and its HA component can still be dissolved with hyaluronidase. Example: TOSCANA CaHA+.
A monophasic filler is one uniform, cohesive gel that spreads smoothly; a biphasic filler suspends cross-linked HA particles in a carrier for more lift. Neuramis is monophasic, while VOM combines a monophasic gel with biphasic particles in a multi-layered phasic structure.
Lidocaine, typically 0.3%, is a local anaesthetic mixed into the gel to reduce pain during injection. YVOIRE, Neuramis Lidocaine, The Chaeum, e.p.t.q., Elravie Premier and VOM all contain lidocaine.
BDDE (1,4-butanediol diglycidyl ether) is the cross-linker that turns HA into a long-lasting gel. Manufacturers purify the gel and limit how much BDDE is used: Hugel states residual BDDE in The Chaeum is below 2 ppm, and Jetema's 2CM technology keeps e.p.t.q. at a modification degree of around 1%.
Softer, lower-viscosity gels suit superficial lines (YVOIRE Classic, Neuramis Light Lidocaine, e.p.t.q. S100, VOM Light); firmer, high-viscosity gels suit deep folds and contouring (YVOIRE Contour, Neuramis Volume Lidocaine, The Chaeum No.4, e.p.t.q. S500, Elravie Ultra Volume-L, VOM Volume).
Dermal fillers are supplied only to licensed medical professionals, dermatology and aesthetic clinics, and importers outside Korea.
Email [email protected] with your clinic name, country and the products you are interested in. We will reply with a price list and minimum order details.
Yes — APLE sells for export only and does not supply customers in Korea. Availability depends on each product's registration status in your country; contact us and we will confirm.
Yes. English catalogs and instructions for use are available on request, together with the licence and certification documents that apply to each product (for example Korean MFDS licences and CE certificates). Status varies by product and destination country.
YVOIRE (LG Chem), Neuramis (Medytox), The Chaeum (Hugel), e.p.t.q. (Jetema), Elravie Premier (Humedix), VOM (CGBio) and TOSCANA PLLA, CaHA+ and body fillers.
Get the catalog and wholesale price list for your clinic or distribution business.